De novo recurrent germline mutation of the BRCA2 gene in a patient with early onset breast cancer.

@article{Luijt2001DeNR,
  title={De novo recurrent germline mutation of the BRCA2 gene in a patient with early onset breast cancer.},
  author={Rob B van der Luijt and Patrick H A van Zon and Rumo P. M. Jansen and Carla Van der Sijs-Bos and Carla C. W{\'a}rl{\'a}m-Rodenhuis and Margreet G E M Ausems},
  journal={Journal of medical genetics},
  year={2001},
  volume={38 2},
  pages={102-5}
}
Germline mutations in either of the two major breast cancer predisposition genes, BRCA1 and BRCA2, account for a significant proportion of hereditary breast/ovarian cancer. Identification of breast cancer patients carrying mutations of these genes is primarily based on a positive family history of breast/ovarian cancer or early onset of the disease or both. In the course of mutation screening of the BRCA1 and BRCA2 genes in a hospital based series of patients with risk factors for hereditary… CONTINUE READING
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A prospective study on risk factors for hereditary breast cancer in a hospital - based series of breast cancer patients

  • Ausems MGEM, RB VanderLuijt, Koot VCM
  • Am J Hum Genet
  • 2000

Muta - tion analysis of the BRCA 1 and BRCA 2 genes in a hospital - based series of patients with risk factors for hereditary breast cancer

  • RB VanderLuijt, Jansen RPM, Van Zon PHA
  • Eur J Hum Genet
  • 2000

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