De novo expression of EphA2 in osteosarcoma modulates activation of the mitogenic signalling pathway.

Abstract

AIMS In osteosarcoma patients the development of metastases, often to the lungs, is the most frequent cause of death. The aim of this study was to elucidate the molecular mechanisms governing osteosarcoma development and dissemination and, thereby, to identify possible novel drug targets for improved treatment. METHODS AND RESULTS Osteosarcoma samples… (More)
DOI: 10.1111/j.1365-2559.2010.03713.x

Topics

13 Figures and Tables

Cite this paper

@article{FritscheGuenther2010DeNE, title={De novo expression of EphA2 in osteosarcoma modulates activation of the mitogenic signalling pathway.}, author={Raphaela Fritsche-Guenther and Aurelia Noske and Ute Ungethuem and Ralf-Juergen Kuban and Peter M. Schlag and Per-Ulf Tunn and Janine Karle and V. T. Krenn and Manfred Dietel and Christine Sers}, journal={Histopathology}, year={2010}, volume={57 6}, pages={836-50} }