De novo enzymes by computational design.

Abstract

Computational enzyme design has emerged as a promising tool for generating made-to-order biocatalysts. In addition to improving the reliability of the design cycle, current efforts in this area are focusing on expanding the set of catalyzed reactions and investigating the structure and mechanism of individual designs. Although the activities of de novo… (More)
DOI: 10.1016/j.cbpa.2013.02.012

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