De novo construction of polyploid linkage maps using discrete graphical models

@article{Behrouzi2019DeNC,
  title={De novo construction of polyploid linkage maps using discrete graphical models},
  author={Pariya Behrouzi and Ernst C. Wit},
  journal={Bioinformatics},
  year={2019},
  volume={35},
  pages={1083–1093}
}
MOTIVATION Linkage maps are used to identify the location of genes responsible for traits and diseases. New sequencing techniques have created opportunities to substantially increase the density of genetic markers. Such revolutionary advances in technology have given rise to new challenges, such as creating high-density linkage maps. Current multiple testing approaches based on pairwise recombination fractions are underpowered in the high-dimensional setting and do not extend easily to… 
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9 Citations
Background Citations
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Methods Citations
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9 Citations

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This work used genotyping by sequencing of full-sib progeny to relate genomic regions with brown rust phenotypes by establishing a pipeline to identify reliable SNPs in complex polyploid data, which were used for phenotypic prediction via machine learning.
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