De-escalation therapy in ventilator-associated pneumonia.


PURPOSE OF REVIEW To describe the use of a 'de-escalation' strategy to deliver appropriate empiric therapy for ventilator-associated pneumonia, without the overuse of antibiotics. RECENT FINDINGS Initial empiric therapy can be appropriate in 80-90% of ventilator-associated pneumonia patients, if it is selected on the basis of local microbiologic data or… (More)


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