De Novo Generation and Characterization of New Zika Virus Isolate Using Sequence Data from a Microcephaly Case

@article{Setoh2017DeNG,
  title={De Novo Generation and Characterization of New Zika Virus Isolate Using Sequence Data from a Microcephaly Case},
  author={Y. X. Setoh and N. Prow and Nias Y G Peng and L. Hugo and G. Devine and J. Hazlewood and A. Suhrbier and A. Khromykh},
  journal={mSphere},
  year={2017},
  volume={2}
}
The major complications of an ongoing Zika virus outbreak in the Americas and Asia are congenital defects caused by the virus’s ability to cross the placenta and infect the fetal brain. The ability to generate molecular tools to analyze viral isolates from the current outbreak is essential for furthering our understanding of how these viruses cause congenital defects. The majority of existing viral isolates and infectious cDNA clones generated from them have undergone various numbers of… Expand
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