Daytime variability of postprandial glucose tolerance and pancreatic B-cell function using 12-h profiles in persons with Type 2 diabetes.
@article{Peter2010DaytimeVO,
title={Daytime variability of postprandial glucose tolerance and pancreatic B-cell function using 12-h profiles in persons with Type 2 diabetes.},
author={Rajesh Peter and Gareth J Dunseath and Stephen D. Luzio and Richard A Chudleigh and Subhasis Roy Choudhury and David R. Owens},
journal={Diabetic medicine : a journal of the British Diabetic Association},
year={2010},
volume={27 3},
pages={
266-73
}
}
AIMS
To study the variation in daytime glucose tolerance and pancreatic B-cell function at different levels of glycated haemoglobin (HbA(1c)) in subjects with Type 2 diabetes (T2DM).
METHODS
T2DM subjects (n = 49; 34 men) had 12-h daytime plasma glucose (PG), insulin (PI), total (PTp) and intact proinsulin (PIp) profiles determined in response to three identical test meals at 4-h intervals. Subjects were divided into three groups according to HbA(1c)--group 1: < 7.3% (n = 18); group 2: 7.3-8… CONTINUE READING