Daytime variability of postprandial glucose tolerance and pancreatic B-cell function using 12-h profiles in persons with Type 2 diabetes.

@article{Peter2010DaytimeVO,
  title={Daytime variability of postprandial glucose tolerance and pancreatic B-cell function using 12-h profiles in persons with Type 2 diabetes.},
  author={Rajesh Peter and Gareth J Dunseath and Stephen D. Luzio and Richard A Chudleigh and Subhasis Roy Choudhury and David R. Owens},
  journal={Diabetic medicine : a journal of the British Diabetic Association},
  year={2010},
  volume={27 3},
  pages={
          266-73
        }
}
AIMS To study the variation in daytime glucose tolerance and pancreatic B-cell function at different levels of glycated haemoglobin (HbA(1c)) in subjects with Type 2 diabetes (T2DM). METHODS T2DM subjects (n = 49; 34 men) had 12-h daytime plasma glucose (PG), insulin (PI), total (PTp) and intact proinsulin (PIp) profiles determined in response to three identical test meals at 4-h intervals. Subjects were divided into three groups according to HbA(1c)--group 1: < 7.3% (n = 18); group 2: 7.3-8… CONTINUE READING

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