Davallialactone protects against adriamycin-induced cardiotoxicity in vitro and in vivo

Abstract

Adriamycin (ADR) is a potent anticancer drug. Its clinical applications are limited due to its cardiotoxicity. Oxidative stress is responsible for cardiomyopathy induced by ADR. Previous studies have demonstrated that davallialactone (DAVA), extracted from mushroom Inonotus xeranticus, has potential antiplatelet aggregation activity and free radical… (More)
DOI: 10.1007/s11418-011-0567-1

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