Daucane sesquiterpenes from Ferula hermonis.

@article{Lhuillier2005DaucaneSF,
  title={Daucane sesquiterpenes from Ferula hermonis.},
  author={Am{\'e}lie Lhuillier and N. Fabre and Edmond Cheble and Fathi Oueida and S. Maurel and A. Valentin and I. Fourast{\'e} and C. Moulis},
  journal={Journal of natural products},
  year={2005},
  volume={68 3},
  pages={
          468-71
        }
}
The dried roots of Ferula hermonis yielded three new daucanes, (1R,4R)-4-hydroxydauca-7-ene-6-one (1), (1R,4R)-4-hydroxydauca-7-ene-6,9-dione (2), and (1R,3S,8S)-3-ethoxy-8-angeloyloxydauca-4-en-9-one (3), together with the three known sesquiterpenes, ferutinin, teferidin, and (+)-alpha-bisabolol. The structures of compounds 1-3 were elucidated on the basis of spectroscopic evidence. The effect of these compounds on the proliferation of estrogen-dependent MCF-7 cells was evaluated, and it was… Expand
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