Datura metel Administration Distorts Medial Prefrontal Cortex Histology of Wistar Rats

  title={Datura metel Administration Distorts Medial Prefrontal Cortex Histology of Wistar Rats},
  author={Temitope Akhigbe Etibor and Musa Iyiola Ajibola and Mohammad Olanrewaju Buhari and Abass Alao Safiriyu and Oluwole Busayo Akinola and Ezekiel Ademola Caxton-Martins},
Datura metel is one of psychoactive substances of great ethno-pharmacological significance often abused because of its unrestricted availability, yet, little is known about its mechanisms of action. This work was therefore aimed at assessing the activity of ethanolic seed extract of D. metel on Nissl substances, astrocytes, axonal and neuronal integrity of the medial prefrontal cortex (mPFC) of Wistar rats. Eighteen Wistar rats averaging 175 g were used and randomly assigned to three groups… CONTINUE READING
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