Daten zur Spermienpenetration im Cervikalschleim unter der Einnahme der Zweiphasen-Präparate Ovanon® und Sequilar®

  title={Daten zur Spermienpenetration im Cervikalschleim unter der Einnahme der Zweiphasen-Pr{\"a}parate Ovanon{\textregistered} und Sequilar{\textregistered}},
  author={K. Bregulla and M. Fr{\"o}hlich},
  journal={Archiv f{\"u}r Gyn{\"a}kologie},
SummaryThe in vitro penetrability of cervical mucus by sperm was investigated in women who were taking Ovanon or Sequilar. Measurements were made under constant experimental conditions on every day of the cycle. The depth of penetration differed strikingly between women with normal menstrual cycles and women taking the sequential hormonal contraceptives. The penetration depth was substantially less when Sequilar or Ovanon was used. The Sequilar induced cervical sperm barrier during the entire… Expand
1 Citations
Local collagen turnover in human foetal membranes during full term vaginal delivery.
Term rupture of foetal membranes is accompanied by increased local degradation of type I collagen fibrils at the rupture site, whereas the biosynthesis of collagen types I and III remains unchanged. Expand


Prevention of sperm migration into the uterine cavity by a microdose progestagen.
  • M. Roland
  • Biology, Medicine
  • Fertility and sterility
  • 1970
Investigation of the capacitation process a prerequisite for fertilization in various mammalian species but not known in human reproduction is discussed using Norgestrol a totally synthesized gonaneExpand
Results of in vitro sperm penetration tests in cervical mucus in the normal cycle and in mucus under the influence of the contraceptive pill
This study of the depth of penetration of the spermatozoa in relation to the hormonal situation was prompted not by contraceptive but rather by epidemiological considerations of cervical carcinoma. Expand
Norgestrel-induced cervical barrier to sperm migration.
It has been postulated that sperm capacitation may be initiated in the cervical canal and to elucidate the possible function of a new totally synthetic progestagen which when administered in microdoses without estrogen appears to suppress fertility. Expand
Effect of minipills on physiologic responses of human cervical mucus, endometrium, and ovary.
It is concluded that low-dose progestogens achieve their contraceptive effect through interference with sperm migration in the cervical mucus alteration of endometrial morphology and possible interference with hormonal equilibrium. Expand
In vitro Sperm migration in the human cervical mucus with different contraceptive methods
It was noticeable, however, that sperm penetration does not become abolished in the progestagen group up to 3–4 cm from the sperm-mucus contact point: at this distance a “STOP” of migration was constantly observed. Expand
Influence of various hormonal contraceptives on sperm migration in vivo.
Results show that the estrogens used increased intercervical penetrability but had no action on intrauterine sperm penetration, which may account for the contraceptive effect of low-dose progestational agents. Expand
Cervical mucus penetration in vitro by fresh and frozen-preserved human semen specimens.
This capillary tube test has been shown to be a reasonably reliable predictor of the fertility of fresh human spermatozoa. Expand
The Origin and Nature of Premalignant Lesions of the Cervix Uteri
The search for the etiology of squamous cancer of the uterine cervix and its antecedent cond itions has received fresh impetus from two sources: the epidemiologist increasingly insistent that the disease is coital in origin and the experimental cancer biologist gene rat ing new co ncepts regarding t he carcinogenic process. Expand
Determination of sperm migration rate in small samples of cervical mucus.
An attempt was made to modify a glass capillary test for sperm penetration to enable repeated tests of sperm penetration in the same sample of cervical mucus (cxm) and the assessment of penetrationExpand
Danazol--a synthetic steroid derivative with interesting physiologic properties.
The antigonadotropic antiandrogenic and androgenic estrogenic antiestrogenic progestational and antiprogestational activities of Danazol were investigated in rats mice and rabbits and the compound demonstrated a weak mytrophic effect. Expand