Database screening and in vivo efficacy of antimicrobial peptides against methicillin-resistant Staphylococcus aureus USA300.

@article{Menousek2012DatabaseSA,
  title={Database screening and in vivo efficacy of antimicrobial peptides against methicillin-resistant Staphylococcus aureus USA300.},
  author={Joseph Menousek and Biswajit Mishra and Mark L. Hanke and Cortney E. Heim and Tammy L. Kielian and Guangshun Wang},
  journal={International journal of antimicrobial agents},
  year={2012},
  volume={39 5},
  pages={402-6}
}
Natural antimicrobial peptides (AMPs) are promising candidates for developing a generation of new antimicrobials to meet the challenge of antibiotic-resistant pathogens such as methicillin-resistant Staphylococcus aureus (MRSA). To facilitate the search for new candidates, we have utilised the Antimicrobial Peptide Database (APD), which contains natural AMPs from bacteria, fungi, plants and animals. This study demonstrates the identification of novel templates against MRSA by screening 30… CONTINUE READING

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Antimicrobial peptides: discovery, design and novel therapeutic strategies

  • G. Wang
  • 2010
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