Data from complete mtDNA sequencing of Tunisian centenarians: Testing haplogroup association and the “golden mean” to longevity

  title={Data from complete mtDNA sequencing of Tunisian centenarians: Testing haplogroup association and the “golden mean” to longevity},
  author={M. D. Costa and L. Cherni and V. Fernandes and F. Freitas and L. Pereira},
  journal={Mechanisms of Ageing and Development},
  • M. D. Costa, L. Cherni, +2 authors L. Pereira
  • Published 2009
  • Biology, Medicine
  • Mechanisms of Ageing and Development
  • Since the mitochondrial theory of ageing was proposed, mitochondrial DNA (mtDNA) diversity has been largely studied in old people, however complete genomes are still rare, being limited to Japanese and UK/US samples. In this work, we evaluated possible longevity associated polymorphisms/haplogroups in an African population, from Tunisia, by performing complete mtDNA sequencing. This population has a mixed Eurasian/sub-Saharan mtDNA gene pool, which could potentially facilitate the evaluation of… CONTINUE READING
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