• DOI:10.1016/j.mad.2008.12.001
Corpus ID: 6102820

Data from complete mtDNA sequencing of Tunisian centenarians: Testing haplogroup association and the “golden mean” to longevity

@article{Costa2009DataFC,
  title={Data from complete mtDNA sequencing of Tunisian centenarians: Testing haplogroup association and the “golden mean” to longevity},
  author={M. D. Costa and L. Cherni and V. Fernandes and F. Freitas and L. Pereira},
  journal={Mechanisms of Ageing and Development},
  year={2009},
  volume={130},
  pages={222-226}
}

M. D. Costa, L. Cherni, +2 authors L. Pereira

Published 2009

Biology, Medicine

Mechanisms of Ageing and Development

Since the mitochondrial theory of ageing was proposed, mitochondrial DNA (mtDNA) diversity has been largely studied in old people, however complete genomes are still rare, being limited to Japanese and UK/US samples. In this work, we evaluated possible longevity associated polymorphisms/haplogroups in an African population, from Tunisia, by performing complete mtDNA sequencing. This population has a mixed Eurasian/sub-Saharan mtDNA gene pool, which could potentially facilitate the evaluation of… CONTINUE READING

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