Data-controlled automation of liquid chromatography/tandem mass spectrometry analysis of peptide mixtures.

@article{Stahl1996DatacontrolledAO,
  title={Data-controlled automation of liquid chromatography/tandem mass spectrometry analysis of peptide mixtures.},
  author={Danese C Stahl and Kristine M. Swiderek and Michael T. Davis and Terry D. Lee},
  journal={Journal of the American Society for Mass Spectrometry},
  year={1996},
  volume={7 6},
  pages={532-40}
}
The structural characterization of proteins and peptides isolated in minute quantities requires the most efficient use of available sample. A mass spectrometer data system was programmed to continuously evaluate incoming liquid chromatography/mass spectrometry data against a user-defined array of information. The resulting conclusions were used to automatically set and modify acquisition parameters in real time to collect collision-induced dissociation spectra for selected ions (tandem mass… CONTINUE READING
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