Data characterizing the biophysical and nitric oxide release properties of the tDodSNO – Styrene maleic anhydride nanoparticle SMA-tDodSNO

@article{Alimoradi2018DataCT,
  title={Data characterizing the biophysical and nitric oxide release properties of the tDodSNO – Styrene maleic anhydride nanoparticle SMA-tDodSNO},
  author={Houman Alimoradi and Anita Barzegar-fallah and Ivan A Sammut and Khaled Greish and Gregory I. Giles},
  journal={Data in Brief},
  year={2018},
  volume={21},
  pages={1771 - 1775}
}
Nitric oxide (NO) donor drugs have a range of clinical applications, and are also being developed as therapeutics for the potential treatment of multiple diseases. This article presents data describing the synthesis and characterisation of a novel NO releasing nanoparticle formed by encapsulation of the NO donor tDodSNO into a co-polymer of styrene and maleic acid (SMA) to afford SMA-tDodSNO. The pharmacological activity of SMA-tDodSNO is discussed in our accompanying manuscript “Encapsulation… Expand
2 Citations
Controlled Delivery of Nitric Oxide for Cancer Therapy
TLDR
The effects of NO in cancer biology, NO releasing moieties which can be used for NO delivery, and current advances in the design of NO releasing biomaterials focusing on their applications for tumor therapy are covered. Expand

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