Das fetale Profil im ersten Trimenon – mehr als nur NT

  title={Das fetale Profil im ersten Trimenon – mehr als nur NT},
  author={M. Hoopmann and Karl Oliver Kagan},
  journal={Ultraschall in Der Medizin},
Das midsagittale Profil stellt eine Schlusselebene im Rahmen der sonografischen Ersttrimesterdiagnostik im Zeitraum 11 + 0 bis 13 + 6 SSW dar. Es handelt sich um die zurzeit am besten qualitatsgesicherte pranatale Bildeinstellung. Dem ursprunglichen Zweck der korrekten Messung der Nackentransparenz zur Risikoanalyse auf Aneuploidien konnten in den letzten Jahren zahlreiche zusatzliche Aspekte der fetalen Fehlbildungsdiagnostik hinzugefugt werden. So lassen sich aus dem fetalen Profil neben dem… 
4 Citations

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In this article the longitudinal development of the posterior fossa structures will be reviewed and the embryologic description will be compared with ultrasound descriptions, and these embryologic and anatomic illustrations form the basis for the screening and diagnosis of malformations of the anterior fossa.

The usefulness of noninvasive liver stiffness assessment using shear-wave elastography for predicting liver fibrosis in children

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Pränatale Diagnostik fetaler Neuralrohrdefekte



Detection of Spina Bifida by First Trimester Screening - Results of the Prospective Multicenter Berlin IT-Study.

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Assessment of Pericallosal Arteries by Color Doppler Ultrasonography at 11-14 Weeks: An Early Marker of Fetal Corpus Callosum Development in Normal Fetuses and Agenesis in Cases with Chromosomal Anomalies

The PA can routinely be observed at the first-trimester evaluation with color Doppler ultrasonography using the mid-sagittal view of the fetal head, and the presence of an abnormal vascular map of the PA by Dopples raises the suspicion of corpus callosum agenesis.

Screening for Fetal Spina Bifida Aperta by the Ultrasound and Intracranial Translucency Examinations at 11–13+6 Weeks of Gestation

Ultrasound examination with IT measurement at 11–13+6 weeks of gestation can be used to screen for fetal spina bifida aperta, and the reduction of IT thickness is an indicator of spina BifidaAperta.

Prenatal diagnosis of Blake's pouch cyst following first‐trimester observation of enlarged intracranial translucency

A 27-year-old primigravida with no relevant medical history was seen for her first prenatal appointment and first-trimester ultrasound scan, and it was concluded that the fetus had a persistent Blake’s pouch (or Blake's pouch cyst).

Increased nuchal translucency with normal karyotype.

First‐Trimester Sonographic Findings Associated With a Dandy‐Walker Malformation and Inferior Vermian Hypoplasia

Evaluation of the fourth ventricle‐cisterna magna complex, by measuring the intracranial translucency or brain stem‐to‐occipital bone diameter, may identify some cases with structural malformations of the cerebellum as early as the first trimester.

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This review summarizes the current knowledge of first‐trimester neurosonography in the normal and abnormal fetus and gives an overview of which diseases can be diagnosed.

Principles of first trimester screening in the age of non-invasive prenatal diagnosis: screening for chromosomal abnormalities

Significant advances in screening for trisomy 21 have been made over the past 2 decades and contemporary screening policies can detect for more than 95% of affected fetuses for false positive rate of less than 3%.

Estimation of Detection Rates of Aneuploidy in High-Risk Pregnancy Using an Approach Based on Nuchal Translucency and Non-Invasive Prenatal Testing: A Cohort Study

A policy of NIPT for increased-risk cases and CVS with full karyotype if the NT was ≥3.0 mm reduced the risk of miscarriage yet still identified 95% of clinically significant aneuploidy.

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A number of fetal malformations remain undetected by early ultrasonography because of the natural history of fetal defects and the late development of some organ systems.