Darwinian behavior in a cold, sporadically fed pool of ribonucleotides.

@article{Yarus2012DarwinianBI,
  title={Darwinian behavior in a cold, sporadically fed pool of ribonucleotides.},
  author={M. Yarus},
  journal={Astrobiology},
  year={2012},
  volume={12 9},
  pages={
          870-83
        }
}
  • M. Yarus
  • Published 2012
  • Biology, Medicine
  • Astrobiology
A testable, explicit origin for Darwinian behavior, feasible on a chaotic early Earth, would aid origins discussion. Here I show that a pool receiving unreliable supplies of unstable ribonucleotide precursors can recurrently fill this role. By using numerical integration, the differential equations governing a sporadically fed pool are solved, yielding quantitative constraints for the proliferation of molecules that also have a chemical phenotype. For example, templated triphosphate nucleotide… Expand
A ribonucleotide Origin for Life – Fluctuation and Near-ideal Reactions
  • M. Yarus
  • Biology, Medicine
  • Origins of Life and Evolution of Biospheres
  • 2013
Efficient Heritable Gene Expression Readily Evolves in RNA Pools
  • M. Yarus
  • Biology, Medicine
  • Journal of Molecular Evolution
  • 2017
Dynamics of prebiotic RNA reproduction illuminated by chemical game theory
The Stereochemical Basis of the Genetic Code and the (Mostly) Autotrophic Origin of Life
Constraint Closure Drove Major Transitions in the Origins of Life
Poly(U) RNA-templated synthesis of AppA.
...
1
2
...

References

SHOWING 1-10 OF 48 REFERENCES
From replicators to reproducers: the first major transitions leading to life.
The stability of the RNA bases: implications for the origin of life.
  • M. Levy, S. Miller
  • Medicine, Biology
  • Proceedings of the National Academy of Sciences of the United States of America
  • 1998
Rates of decomposition of ribose and other sugars: implications for chemical evolution.
Acyl-CoAs from coenzyme ribozymes.
Origins of the genetic code: the escaped triplet theory.
Survival of replicators with parabolic growth tendency and exponential decay.
...
1
2
3
4
5
...