Dark- and light-induced changes in coupling between horizontal cells in mammalian retina.

@article{Xin1999DarkAL,
  title={Dark- and light-induced changes in coupling between horizontal cells in mammalian retina.},
  author={D. Xin and Stewart A. Bloomfield},
  journal={The Journal of comparative neurology},
  year={1999},
  volume={405 1},
  pages={75-87}
}
Retinal horizontal cells exhibit large receptive fields derived from their extensive electrical coupling by means of gap junctions. The conductance of these gap junctions seems to be regulated by dopamine acting through a cAMP-mediated cascade. There is now abundant evidence that extracellular dopamine levels vary with changes in ambient light intensity, suggesting that changes in the dark/light adaptational state of the retina can modulate coupling between horizontal cells. We studied this… CONTINUE READING

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