Dark adaptation of rod photoreceptors in normal subjects, and in patients with Stargardt disease and an ABCA4 mutation.

@article{Derwent2004DarkAO,
  title={Dark adaptation of rod photoreceptors in normal subjects, and in patients with Stargardt disease and an ABCA4 mutation.},
  author={Jennifer J Kang Derwent and Deborah J. Derlacki and John R. Hetling and Gerald Allen Fishman and David G. Birch and Sandeep Grover and Edwin M. Stone and David R. Pepperberg},
  journal={Investigative ophthalmology & visual science},
  year={2004},
  volume={45 7},
  pages={2447-56}
}
PURPOSE Psychophysical and electroretinographic (ERG) studies indicate that patients with Stargardt disease exhibit abnormally slow rod dark adaptation after illumination that bleaches a substantial fraction of rhodopsin. However, relatively little information is available concerning rod recovery in this disease after weaker adapting (i.e., conditioning… CONTINUE READING