• Corpus ID: 29208007

Dapoxetine: LY 210448.

  title={Dapoxetine: LY 210448.},
  journal={Drugs in R\&D},
  volume={6 5},
  • Published 2005
  • Medicine
  • Drugs in R&D
Dapoxetine [LY 210448], a selective serotonin reuptake inhibitor (SSRI), is structurally related to fluoxetine with antidepressant activity. Dapoxetine is the D-enantiomer of LY 243917 and is 3.5 times more potent as a serotonin reuptake inhibitor than the L-enantiomer. Dapoxetine was in phase I clinical trials in the US with Eli Lilly as an antidepressant, but no recent development has been reported for this indication. However, development is underway for the treatment of premature… 
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