Daphnane diterpenes from Diarthron vesiculosum: vesiculosin and isovesiculosin.

  title={Daphnane diterpenes from Diarthron vesiculosum: vesiculosin and isovesiculosin.},
  author={R. G. Powell and D. Weisleder and C. R. Smith},
  journal={Journal of natural products},
  volume={48 1},
  • R. G. Powell, D. Weisleder, C. R. Smith
  • Published 1985
  • Biology, Medicine
  • Journal of natural products
  • An alcoholic extract of Diarthron vesiculosum seed has yielded two novel daphnane diterpene esters, vesiculosin and isovesiculosin. Compounds 1 and 2 undergo rapid interconversion to an equilibrium mixture containing approximately 80% 1 and 20% 2 in solution at elevated temperatures. At 25 degrees or below, 1 and 2 may be isolated and stored for extended periods with minimal interconversion. Excoecariatoxin and simplexin are the major daphnane orthoesters present in D. vesiculosum, and 1 and 2… CONTINUE READING
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