Dapagliflozin improves glycemic control and reduces body weight as add-on therapy to metformin plus sulfonylurea: a 24-week randomized, double-blind clinical trial.

@article{Matthi2015DapagliflozinIG,
  title={Dapagliflozin improves glycemic control and reduces body weight as add-on therapy to metformin plus sulfonylurea: a 24-week randomized, double-blind clinical trial.},
  author={Stephan Matth{\"a}i and Keith Bowering and Katja Rohwedder and Anke Grohl and Shamik J. Parikh},
  journal={Diabetes care},
  year={2015},
  volume={38 3},
  pages={365-72}
}
OBJECTIVE To evaluate the efficacy and safety of dapagliflozin in patients with type 2 diabetes inadequately controlled with metformin and sulfonylurea. RESEARCH DESIGN AND METHODS Patients with HbA1c of 7.0% (53 mmol/mol) to 10.5% (91 mmol/mol) receiving sulfonylurea and metformin were randomized to receive dapagliflozin 10 mg/day (n = 109) or placebo (n = 109) for 24 weeks. RESULTS HbA1c (baseline: dapagliflozin 8.08% [65 mmol/mol]; placebo 8.24% [67 mmol/mol]) and fasting plasma glucose… CONTINUE READING
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Dapagli - fl ozin in patients with type 2 diabetes receiving high doses of insulin : ef fi cacy and safety over 2 years

  • J Shao, B Zhong
  • Diabetes Obes Metab
  • 2014

Dapagli fl ozin is effective as add - on therapy to sitagliptin with or without metformin : a 24 - week , multicenter , randomized , double - blind , placebo - controlled study

  • MA Nauck, S DelPrato, JJ Meier
  • Diabetes Care
  • 2014

( Abstract )

  • HU Häring, L Merker, E Seewaldt-Becker
  • 2013

Dapagliflozin as part of triple combination therapy helps reduce HbA1c and body weight in patients with type 2 diabetes (Abstract)

  • S Jabbour, E Hardy, T DeBruin
  • Diabetes 2013; 62(Suppl
  • 2013
1 Excerpt

Dapagliflozin effects on the lipid profile of patients with type 2 diabetes mellitus (Abstract)

  • E Hardy, A Ptaszynska, T DeBruin, E Johnsson, S Parikh, J. List
  • Diabetes 2013;62(Suppl
  • 2013
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