Danger in the reef: Proteome, toxicity, and neutralization of the venom of the olive sea snake, Aipysurus laevis.

@article{Laustsen2015DangerIT,
  title={Danger in the reef: Proteome, toxicity, and neutralization of the venom of the olive sea snake, Aipysurus laevis.},
  author={Andreas Hougaard Laustsen and Jos{\'e} Mar{\'i}a Guti{\'e}rrez and Arne R Rasmussen and Mikael Engmark and Peter Gravlund and Kate L. Sanders and Brian Lohse and Bruno Lomonte},
  journal={Toxicon : official journal of the International Society on Toxinology},
  year={2015},
  volume={107 Pt B},
  pages={
          187-96
        }
}
Four specimens of the olive sea snake, Aipysurus laevis, were collected off the coast of Western Australia, and the venom proteome was characterized and quantitatively estimated by RP-HPLC, SDS-PAGE, and MALDI-TOF-TOF analyses. A. laevis venom is remarkably simple and consists of phospholipases A2 (71.2%), three-finger toxins (3FTx; 25.3%), cysteine-rich secretory proteins (CRISP; 2.5%), and traces of a complement control module protein (CCM; 0.2%). Using a Toxicity Score, the most lethal… CONTINUE READING
Related Discussions
This paper has been referenced on Twitter 1 time. VIEW TWEETS

Citations

Publications citing this paper.
Showing 1-3 of 3 extracted citations

Toxin synergism in snake venoms

Andreas Hougaard
2017
View 8 Excerpts
Highly Influenced

References

Publications referenced by this paper.
Showing 1-10 of 44 references

The nephrotoxicity of fractionated components of Aipysurus laevis venom.

Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie • 1997
View 5 Excerpts
Highly Influenced

Proteomic tools against the neglected pathology of snake bite envenoming.

Expert review of proteomics • 2011
View 2 Excerpts
Highly Influenced

The in vitro

N. Chetty, A. Du, W. C. Hodgson, K. D. Winkel, B. G. Fry
2004
View 3 Excerpts
Highly Influenced

Feeding strategies in marine snakes: an analysis

H. K. Voris, H. H. Voris
1983
View 2 Excerpts
Highly Influenced

Attacks by sea snakes on divers

H. Heatwole
1975
View 4 Excerpts
Highly Influenced

Feeding behavior of Indo-Australian Hydrophiidae

J. E. McCosker
1975
View 3 Excerpts
Highly Influenced

Sea snakes of Australia and New Guinea. In: The Biology of Sea

H. G. Cogger
1975
View 5 Excerpts
Highly Influenced

Danger in the reef : proteome , toxicity , and neutralization of the venom of the olive sea snake , Aipysurus laevis

J. M. Gutiérrez, A. Redsted Rasmussen, +3 authors B. Lomonte
Toxicon • 2015