Danger Signals in the Initiation of the Inflammatory Response after Myocardial Infarction

@inproceedings{Haan2013DangerSI,
  title={Danger Signals in the Initiation of the Inflammatory Response after Myocardial Infarction},
  author={Judith Jeanette de Haan and Mirjam B. Smeets and G. Pasterkamp and Fatih Arslan},
  booktitle={Mediators of inflammation},
  year={2013}
}
During myocardial infarction, sterile inflammation occurs. The danger model is a solid theoretic framework that explains this inflammation as danger associated molecular patterns activate the immune system. The innate immune system can sense danger signals through different pathogen recognition receptors (PRR) such as toll-like receptors, nod-like receptors and receptors for advanced glycation endproducts. Activation of a PRR results in the production of cytokines and the recruitment of… CONTINUE READING