Dances with black widow spiders: dysregulation of glutamate signalling enters centre stage in ADHD.

@article{Lesch2013DancesWB,
  title={Dances with black widow spiders: dysregulation of glutamate signalling enters centre stage in ADHD.},
  author={Klaus-Peter Lesch and S{\"o}ren Merker and Andreas Reif and Mario Novak},
  journal={European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology},
  year={2013},
  volume={23 6},
  pages={479-91}
}
Attention-deficit/hyperactivity disorder (ADHD) is a common neurodevelopmental disorder with impairments across the lifespan. The persistence of ADHD is associated with considerable liability to neuropsychiatric co-morbidity such as depression, anxiety and substance use disorder. The substantial heritability of ADHD is well documented and recent genome-wide analyses for risk genes revealed synaptic adhesion molecules (e.g. latrophilin-3, LPHN3; fibronectin leucine-rich repeat transmembrane… CONTINUE READING