Danazol increases T regulatory cells in patients with aplastic anemia.

@article{Khurana2018DanazolIT,
  title={Danazol increases T regulatory cells in patients with aplastic anemia.},
  author={Harshit Khurana and Pankaj Malhotra and Man Updesh Singh Sachdeva and N. Rajasekhar Varma and Parveen Bose and Uday Yanamandra and Subhash Chander Varma and Alka Rani Khadwal and Deepesh Lad and Gaurav Prakash},
  journal={Hematology},
  year={2018},
  pages={1-5}
}
OBJECTIVES Danazol is an attenuated androgen and is used in the treatment of aplastic anemia (AA) in resource constraint settings. We chose to study the role of CD4+ CD25high CD127low FoxP3+ T regulatory cells (T-regs) in the pathophysiology of AA and their response to treatment with Danazol alone or in combination with immunosuppressive treatment (IST… CONTINUE READING