Damage to the intestinal epithelial barrier by antibiotic pretreatment of salmonella-infected rats is lessened by dietary calcium or tannic acid.

@article{Ampting2010DamageTT,
  title={Damage to the intestinal epithelial barrier by antibiotic pretreatment of salmonella-infected rats is lessened by dietary calcium or tannic acid.},
  author={Marleen T J van Ampting and Arjan J. Schonewille and Carolien Vink and Robert Jan M Brummer and Roelof van der Meer and Ingeborg M. J. Bovee-Oudenhoven},
  journal={The Journal of nutrition},
  year={2010},
  volume={140 12},
  pages={2167-72}
}
Perturbation of the intestinal microbiota by antibiotics predisposes the host to food-borne pathogens like Salmonella. The effects of antibiotic treatment on intestinal permeability during infection and the efficacy of dietary components to improve resistance to infection have not been studied. Therefore, we investigated the effect of clindamycin on intestinal barrier function in Salmonella-infected rats. We also studied the ability of dietary calcium and tannic acid to protect against… CONTINUE READING
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