Damage to human erythrocytes by radiation-generated HO* radicals: molecular changes in erythrocyte membranes.

@article{SzwedaLewandowska2003DamageTH,
  title={Damage to human erythrocytes by radiation-generated HO* radicals: molecular changes in erythrocyte membranes.},
  author={Zofia Szweda-Lewandowska and Anita Krokosz and Marta Gonciarz and Wieslawa Zajeczkowska and Mieczysław Puchała},
  journal={Free radical research},
  year={2003},
  volume={37 10},
  pages={1137-43}
}
The effectiveness of radiation-generated HO* radicals in initiating erythrocyte hemolysis in the presence of oxygen and under anaerobic conditions and prehemolytic structural changes in the plasma-erythrocyte membrane were studied. Under anaerobic conditions the efficacy of HO* radicals in induction of hemolysis was 16-fold lower than under air. In both conditions, hemolysis was the final consequence of changes of the erythrocyte membrane. Preceding hemolysis, the dominating process under… CONTINUE READING
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