Damage and regeneration of hair cell ciliary bundles in a fish ear following treatment with gentamicin

  title={Damage and regeneration of hair cell ciliary bundles in a fish ear following treatment with gentamicin},
  author={A. Lombarte and H. Yan and A. Popper and J. S. Chang and C. Platt},
  journal={Hearing Research},
  • A. Lombarte, H. Yan, +2 authors C. Platt
  • Published 1993
  • Biology, Medicine
  • Hearing Research
  • Sensory hair cells in the striolar regions of the utricle and lagena of a teleost fish, the oscar (Astronotus ocellatus), were damaged following intramuscular injections of gentamicin sulfate. In order to determine whether fish can regenerate hair cells, the time course of damage and recovery was followed over a period of four weeks by scanning electron microscopy. Maximum loss of ciliary bundles occurred at about day 10 after the first of four daily injections of gentamicin (20 mg/kg) in 4-6… CONTINUE READING
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