Damage and recovery of the ovary in female zebrafish i.p.-injected with MC-LR.

@article{Hou2014DamageAR,
  title={Damage and recovery of the ovary in female zebrafish i.p.-injected with MC-LR.},
  author={Jie Hou and Li Li and Ting Xue and Meng Long and Yujing Su and Ning Wu},
  journal={Aquatic toxicology},
  year={2014},
  volume={155},
  pages={110-8}
}
Up to now, in vivo studies on toxic effects of microcystins (MCs) on the reproductive system are limited and the underlying molecular mechanisms of MCs-induced reproductive toxicity remain to be elucidated. In an acute toxic experiment, female zebrafish (Danio rerio) were injected intraperitoneally (i.p.) at doses of 50 and 200 μg MC-LR/kg body weight (BW) respectively, and histopathological lesions and antioxidant enzymatic activities and gene expression in the ovary were studied at 1, 3, 12… CONTINUE READING
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