Dam inactivation in Neisseria meningitidis: prevalence among diverse hyperinvasive lineages

@article{Jolley2004DamII,
  title={Dam inactivation in Neisseria meningitidis: prevalence among diverse hyperinvasive lineages},
  author={Keith A. Jolley and Li Sun and E . Richard Moxon and Martin C J Maiden},
  journal={BMC Microbiology},
  year={2004},
  volume={4},
  pages={34 - 34}
}
DNA adenine methyltransferase (Dam) activity is absent in many, but not all, disease isolates of Neisseria meningitidis, as a consequence of the insertion of a restriction endonuclease-encoding gene, the 'dam replacing gene' (drg) at the dam locus. Here, we report the results of a survey to assess the prevalence of drg in a globally representative panel of disease-associated meningococci. Of the known meningococcal hyper-invasive lineages investigated, drg was absent in all representatives of… CONTINUE READING

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Population genetics and molecular epidemiology of Neisseria meningitidis.

APMIS : acta pathologica, microbiologica, et immunologica Scandinavica • 1998
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