Dam-dependent phase variation of Ag43 in Escherichia coli is altered in a seqA mutant.

Abstract

In Escherichia coli, phase variation of the outer membrane protein Ag43 encoded by the agn43 gene is mediated by DNA methylation and the global regulator OxyR. Transcription of agn43 occurs (ON phase) when three Dam target sequences in the agn43 regulatory region are methylated, which prevents the repressor OxyR from binding. Conversely, transcription is… (More)

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Cite this paper

@article{Correnti2002DamdependentPV, title={Dam-dependent phase variation of Ag43 in Escherichia coli is altered in a seqA mutant.}, author={Jason M Correnti and Vincent Jacobus Munster and Teresa M. Chan and Marjan van der Woude}, journal={Molecular microbiology}, year={2002}, volume={44 2}, pages={521-32} }