Daily variation of serum acylcarnitines and amino acids

  title={Daily variation of serum acylcarnitines and amino acids},
  author={D. K. Thompson and R. Sloane and J. Bain and R. Stevens and C. Newgard and C. Pieper and V. Kraus},
  • D. K. Thompson, R. Sloane, +4 authors V. Kraus
  • Published 2011
  • Medicine
  • Metabolomics
  • To characterize daily variation of amino acids (AAs) and acylcarnitines (ACs) in response to feeding and activity, we measured serum metabolites at various times and after various activities during the day. Subjects were admitted overnight for serial serum sampling, collected in the evening (6–8 p.m., n = 40), before rising from bed or eating (8 a.m., n = 40), 1 h after rising but before eating (9 a.m., n = 20), 1–2 h after rising and breakfast (9–10 a.m., n = 40), and at noon (12 p.m., n = 20… CONTINUE READING
    25 Citations

    Figures, Tables, and Topics from this paper.

    Daily variation and effect of dietary folate on urinary pteridines
    • 6
    Pre-Analytical Factors that Affect Metabolite Stability in Human Urine, Plasma, and Serum: A Review
    • 18
    • PDF
    Association of Plasma Small-Molecule Intermediate Metabolites With Age and Body Mass Index Across Six Diverse Study Populations.
    • 16
    • PDF


    Plasma acylcarnitines are associated with physical performance in elderly men.
    • H. Lum, R. Sloane, +10 authors M. Morey
    • Medicine
    • The journals of gerontology. Series A, Biological sciences and medical sciences
    • 2011
    • 30
    • PDF
    Individual variation in macronutrient regulation measured by proton magnetic resonance spectroscopy of human plasma.
    • Youngja Park, S. Kim, +7 authors D. Jones
    • Chemistry, Medicine
    • American journal of physiology. Regulatory, integrative and comparative physiology
    • 2009
    • 33
    • PDF
    Comparison of amino acids and acylcarnitines assay methods used in newborn screening assays by tandem mass spectrometry.
    • 48
    Diurnal rhythm in absolute and relative concentrations of large neutral amino acids in human plasma.
    • 32
    • Highly Influential
    Acylcarnitines: analysis in plasma and whole blood using tandem mass spectrometry.
    • 41
    Carnitine and Acylcarnitines
    • 144
    • PDF
    Factors affecting circadian periodicity of blood amino acids in man.
    • 78
    Variation of serum hyaluronan with activity in individuals with knee osteoarthritis.
    • 33
    Relationships Between Circulating Metabolic Intermediates and Insulin Action in Overweight to Obese, Inactive Men and Women
    • 302
    • PDF