Daily parathyroid hormone administration enhances bone turnover and preserves bone structure after severe immobilization‐induced bone loss

@inproceedings{Harlow2017DailyPH,
  title={Daily parathyroid hormone administration enhances bone turnover and preserves bone structure after severe immobilization‐induced bone loss},
  author={Lauren M. Harlow and Karim Sahbani and Jeffry S Nyman and C P Cardozo and William A. Bauman and Hesham A. W. Tawfeek},
  booktitle={Physiological reports},
  year={2017}
}
Immobilization, as a result of motor-complete spinal cord injury (SCI), is associated with severe osteoporosis. Whether parathyroid hormone (PTH) administration would reduce bone loss after SCI remains unclear. Thus, female mice underwent sham or surgery to produce complete spinal cord transection. PTH (80 μg/kg) or vehicle was injected subcutaneously (SC) daily starting on the day of surgery and continued for 35 days. Isolated tibias and femurs were examined by microcomputed tomography… CONTINUE READING
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