Daily exercise enhances coronary resistance vessel sensitivity to pharmacological activation.

@article{DiCarlo1989DailyEE,
  title={Daily exercise enhances coronary resistance vessel sensitivity to pharmacological activation.},
  author={Stephen E DiCarlo and Robert W Blair and Vernon S Bishop and Harvey Stone},
  journal={Journal of applied physiology},
  year={1989},
  volume={66 1},
  pages={421-8}
}
The effect of daily exercise on the coronary resistance vessel sensitivity to intracoronary infusion of several pharmacological agents was assessed in 12 conscious adult mongrel dogs. alpha-Adrenergic receptor agonists (norepinephrine and phenylephrine) significantly decreased coronary blood flow velocity. beta 2-Adrenergic receptor agonists (isoproterenol and zinterol) and a metabolic vasodilator (adenosine) significantly increased coronary blood flow velocity. These responses occurred without… CONTINUE READING
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