Daily changes in pentylenetetrazol-induced convulsions and open-field behavior in rats.

Abstract

Susceptibility to pentylenetetrazol (PTZ)-induced clonic convulsions was measured in rats over the 24-hr light-dark cycle at four-hour intervals. The results showed a higher sensitivity to PTZ around 2200 hr. Other groups of rats were exposed to a four-min open-field session. In the first two min of the session the animals were submitted to open-field… (More)

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@article{Eidman1990DailyCI, title={Daily changes in pentylenetetrazol-induced convulsions and open-field behavior in rats.}, author={D S Eidman and Manuela Benedito and J. R. Leite}, journal={Physiology & behavior}, year={1990}, volume={47 5}, pages={853-6} }