Daily and circadian variations in 2-[125I]-iodomelatonin binding sites in the pike brain (Esox lucius).

@article{Gaildrat1998DailyAC,
  title={Daily and circadian variations in 2-[125I]-iodomelatonin binding sites in the pike brain (Esox lucius).},
  author={Pascaline Gaildrat and Benny Ron and Jack Falc{\'o}n},
  journal={Journal of neuroendocrinology},
  year={1998},
  volume={10 7},
  pages={511-7}
}
The fish pineal organ, through its 24 h rhythmic release of melatonin, acts as a transducer of the photoperiod, influencing different physiological functions (e.g. reproduction, growth). We have investigated the binding of 2-[125I]iodomelatonin to whole brain membrane preparations from pikes (Esox lucius L., teleost) maintained for 24-48 h under different photoperiodic conditions. Specific binding was stable, reversible, saturable and sensitive to the presence of a GTP analogue. Scatchard… CONTINUE READING

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