Daily Assessment of Pain in Adults with Sickle Cell Disease

@article{Smith2008DailyAO,
  title={Daily Assessment of Pain in Adults with Sickle Cell Disease},
  author={Wally R. Smith and L. Penberthy and V. Bovbjerg and D. McClish and John D. Roberts and B. Dahman and I. Aisiku and J. Levenson and S. Roseff},
  journal={Annals of Internal Medicine},
  year={2008},
  volume={148},
  pages={94-101}
}
Context Although outpatient, emergency department, and hospital visits have been used as indicators of sickle cell disease severity, the relationship between health care use and pain episodes has not been well described. Contribution Two hundred thirty-two patients with sickle cell disease completed a daily diary for 6 months, providing 31017 patient-days for analysis. Patients reported pain on 56% of total patient-days, crises on 13%, and health care utilization on 4%. Implication Patients… Expand

Paper Mentions

Interventional Clinical Trial
The primary aim of this study is to evaluate the effect of the drug N-Acetylcysteine on the frequency of pain in daily life in patients with Sickle Cell Disease (SCD). Pain is… Expand
ConditionsSickle Cell Disease
InterventionDrug
Daily pain in adults with sickle cell disease—a different perspective
TLDR
This first European study on pain in SCD indicates that pain appears to be significantly less frequent in the population as compared to previous study cohorts from the United States, and may be more representative for current SCD populations in other Western countries. Expand
Sickle Cell Disease and Pain
TLDR
Female sex, the presence of current leg ulcers, and the use of a strong opioid in the last 4 weeks produced higher odds of NP, whereas older age, milder genotypes, and daily analgesic use had the highest odds of CP. Expand
WEB-BASED MONITORING OF PAIN MANAGEMENT IN ADOLESCENT AND YOUNG ADULT SICKLE CELL PATIENTS THROUGH DAILY SELF-ASSESSMENT
TLDR
The implementation of a web-based application to monitor daily pain levels is relevant to public health because it is likely to provide medical teams with the tools necessary to track patient pain levels more precisely and to enable healthcare providers to be more proactive with regard to pain management in patients with SCD. Expand
Chronic pain persists in adults with sickle cell disease despite regular red cell transfusions.
  • M. Karafin, Danielle E Mullins, +4 authors J. Field
  • Medicine
  • Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis
  • 2019
TLDR
These results suggest that, even with regular transfusions and a low HbS, daily pain persists in many adults with SCD. Expand
Acute pain in children and adults with sickle cell disease: management in the absence of evidence-based guidelines
TLDR
The epidemiology and management strategies of acute pain events are examined, and limitations in the best available studies are identified. Expand
Pain Management Issues as Part of the Comprehensive Care of Patients with Sickle Cell Disease
TLDR
Providing more appropriate medication and optimal dosage based on individual's genomic variations is the future of medicine, and this will allow the physicians to hone in on optimal pain management in patients with SCD. Expand
Sickle cell disease: a natural model of acute and chronic pain.
TLDR
A 19-year-old female patient with severe sickle cell disease (SCD) presented to her hematologist with severe pain, which significantly increased in frequency and severity between 16 and 19 years with 10 hospitalizations, and she reported almost daily pain. Expand
Five lessons learned about long-term pain management in adults with sickle cell disease.
  • J. Field
  • Medicine
  • Hematology. American Society of Hematology. Education Program
  • 2017
TLDR
These lessons form the basis for the model to manage chronic pain in adults with SCD, and should be seen as an opportunity to more effectively manage the authors' patient's pain in the safest manner possible. Expand
Pain in sickle cell disease: the future of acute treatment
TLDR
Advances in pain management for VOC must begin with an expanded definition of a VOC, and pre-emptive acute remittive drugs might be administered at home prior to hospitalization for V OC, saving money, pain and tissue damage. Expand
Sickle-cell pain: advances in epidemiology and etiology.
New epidemiological findings recast pain in sickle-cell disease (SCD) as being more often a chronic manifestation than was previously thought, although acute pain is still the hallmark of theExpand
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 54 REFERENCES
Understanding pain and improving management of sickle cell disease: the PiSCES study.
TLDR
The Pain in Sickle Cell Epidemiology Study (PiSCES) attempts to develop and validate a biopsychosocial model of SCD pain, pain response and healthcare utilization in a large, multisite adult cohort, suggesting targets for biobehavioral interventions over time. Expand
Gender differences in pain and healthcare utilization for adult sickle cell patients: The PiSCES Project.
TLDR
Contrary to many studies of pain, particularly chronic pain, men and women with SCD reported generally similar pain experiences. Expand
Pain and stress in sickle cell disease: An analysis of daily pain records
TLDR
Stress had significant positive associations with average pain intensity as well as reductions in household and social activities in adults with sickle cell disease, and stress predicted activity reductions even after controlling for pain intensity. Expand
Vaso-Occlusion in Children With Sickle Cell Disease: Clinical Characteristics and Biologic Correlates
TLDR
The authors suggest that vaso-occlusive pain episodes managed at home are more frequent then those resulting in acute care management but likely share a common pathophysiology. Expand
Pain in sickle cell disease. Rates and risk factors.
TLDR
The "pain rate" is a measure of clinical severity and correlates with early death in patients with sickle cell anemia over the age of 20, and even when the fetal hemoglobin level is low, one can predict that small increments in the level may have an ameliorating effect on the pain rate and may ultimately improve survival. Expand
Pain in Children and Adolescents With Sickle Cell Disease: An Analysis of Daily Pain Diaries
TLDR
The results indicate that children with SCD usually experienced low levels of pain that was managed at home, sometimes without any medications, and as pain levels increased, children were more likely to use narcotic medications and health care services, although overall health care utilization during the 2-week period tended to be relatively infrequent. Expand
Pain, quality of life, and coping in sickle cell disease.
This study examined the frequency and severity of sickle related pain, its impact on quality of life, and methods of coping for 25 children with sickle cell disease, aged 6-16 years. Subjects wereExpand
Home management of sickle cell-related pain in children and adolescents: natural history and impact on school attendance
TLDR
A home‐based diary system was developed for children and adolescents with sickle cell disease to gain information about the natural history of the pain and its impact on sleep and school attendance, and age was positively correlated with the length of the painful episodes. Expand
Assessment of painful episode frequency in sickle‐cell disease
TLDR
It is suggested that nonhospital‐related painful episodes and shorter‐lasting episodes may contribute significantly to episode frequency, and measurement of frequency of all painful episodes would require consideration when evaluating episode frequency. Expand
Pain management of sickle cell disease.
  • S. Ballas
  • Medicine
  • Hematology/oncology clinics of North America
  • 2005
TLDR
Management of sickle cell disease continues to be primarily palliative, including supportive, symptomatic, and preventive approaches to therapy, including nonpharmacologic and pharmacologic modalities. Expand
...
1
2
3
4
5
...