Daidzein supplementation decreases serum triglyceride and uric acid concentrations in hypercholesterolemic adults with the effect on triglycerides being greater in those with the GA compared with the GG genotype of ESR-β RsaI.

@article{Qin2014DaidzeinSD,
  title={Daidzein supplementation decreases serum triglyceride and uric acid concentrations in hypercholesterolemic adults with the effect on triglycerides being greater in those with the GA compared with the GG genotype of ESR-β RsaI.},
  author={Yu Qin and Furong Shu and Yuan Zeng and XiangGui Meng and Bin Wang and LiPing Diao and Li Wang and Jing Wan and Jundong Zhu and Jian Wang and Mantian Mi},
  journal={The Journal of nutrition},
  year={2014},
  volume={144 1},
  pages={49-54}
}
Daidzein (one of the major isoflavones) can be metabolized to equol in certain individuals. The effects of isoflavones alone and equol status on lipid profiles are still controversial. To evaluate the 6-mo effects of daidzein on cardiovascular risk factors in hypercholesterolemic individuals and the interactions of these effects with equol status and estrogen receptor (ESR) genotypes, we conducted a randomized, double-blind, placebo-controlled trial consisting of 210 hypercholesterolemic adults… CONTINUE READING
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