Daidzein does affect progesterone secretion by pig cumulus cells but it does not impair oocytes IVM.

@article{Galeati2010DaidzeinDA,
  title={Daidzein does affect progesterone secretion by pig cumulus cells but it does not impair oocytes IVM.},
  author={Giovanna Galeati and Claudia Vallorani and Diego Bucci and Chiara Bernardini and Carlo Tamanini and Albamaria Parmeggiani and Marcella Spinaci},
  journal={Theriogenology},
  year={2010},
  volume={74 3},
  pages={451-7}
}
Daidzein, an isoflavone abundant in soybeans and other legumes, displays estrogen like properties. This study was aimed at evaluating the effect of daidzein (1 and 10 microM) on nuclear and cytoplasmic maturation of pig oocytes and on steroidogenic activity of cumulus cells. Daidzein supplementation during IVM had no effect on nuclear maturation and on fertilization traits. By contrast, both concentrations significantly (P < 0.05) inhibited progesterone production by cumulus cells after 24 and… CONTINUE READING