Daidzein as an antioxidant of lipid: effects of the microenvironment in relation to chemical structure.

@article{Liang2008DaidzeinAA,
  title={Daidzein as an antioxidant of lipid: effects of the microenvironment in relation to chemical structure.},
  author={Jun Liang and Yu-Xi Tian and Limin Fu and Tian-He Wang and Hai-jun Li and Peng Wang and Rui-Min Han and Jian-Ping Zhang and Leif H Skibsted},
  journal={Journal of agricultural and food chemistry},
  year={2008},
  volume={56 21},
  pages={
          10376-83
        }
}
Isoflavone daidzein (D, pK a1 = 7.47 +/- 0.02 and pK a2 = 9.65 +/- 0.07) was, through a study of the parent compound and its three methyl anisol derivatives 7-methyldaidzein (7-Me-D, pK a = 9.89 +/- 0.05), 4'-methyldaidzein (4'-Me-D, pK a = 7.43 +/- 0.03), and 7,4'-dimethyldaidzein (7,4'-diMe-D), found to retard lipid oxidation in liposomal membranes through two mechanisms: (i) radical scavenging for which the 4'-OH was more effective than the 7-OH group in agreement with the oxidation… CONTINUE READING

References

Publications referenced by this paper.
Showing 1-10 of 41 references

Determination of the differential estrogenicity of isoflavones by E 2EREREdependent gene expression in recombinant yeast and MCF7 human breast cancer cells

C. C. Lin, Y. L. Tsai, C. T. Ho, S. C. Teng
Food Chem . • 2007

Synthesis and characterization of puerarin and the mechanism of derivation reaction

R. M. Han, Y. X. Tian, +3 authors J. P. Zhang
Chem . J . Chin . Uni V . • 2006