DYRK1A genetic variants are not linked to Alzheimer's disease in a Spanish case-control cohort

Abstract

As dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A) has been implicated in the abnormal hyperphosphorylation of tau in Alzheimer's disease (AD) brain, and the development of neurofibrillary tangles, we examined the contribution of this gene to the susceptibility for AD. We examined genetic variations of DYRK1A by genotyping haplotype… (More)
DOI: 10.1186/1471-2350-10-129

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Cite this paper

@inproceedings{VzquezHiguera2009DYRK1AGV, title={DYRK1A genetic variants are not linked to Alzheimer's disease in a Spanish case-control cohort}, author={Jos{\'e} Luis V{\'a}zquez-Higuera and P{\'a}scual Sanchez-Juan and Eloy Rodr{\'i}guez-Rodr{\'i}guez and Ignacio Mateo and Ana Pozueta and Ana Frank and Isabel Sastre and Fernando Valdivieso and Jos{\'e} Berciano and Mar{\'i}a J Bullido and Onofre Combarros}, booktitle={BMC Medical Genetics}, year={2009} }