DVWA gene polymorphisms and osteoarthritis

@inproceedings{Bravat2015DVWAGP,
  title={DVWA gene polymorphisms and osteoarthritis},
  author={Valentina Bravat{\`a} and Luigi Minafra and Giusi Irma Forte and Francesco Paolo Cammarata and Michele Saporito and Filippo Boniforti and Domenico Lio and Maria Carla Gilardi and Cristina Messa},
  booktitle={BMC Research Notes},
  year={2015}
}
Osteoarthritis (OA) is a degenerative joints disorder influenced by genetic predisposition. We reported that rs11718863 DVWA SNP was represented in Sicilian with a more severe Kellgren and Lawrence (KL) radiographic grade, displaying its predictive role as OA marker progression. Here, we describe the DVWA SNPs: rs11718863, rs7639618, rs7651842, rs7639807 and rs17040821 probably able to induce protein functional changes. Sixty-one Sicilian patients with knee OA and 100 healthy subjects were… CONTINUE READING

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