DURAbility of Basal Versus Lispro Mix 75/25 Insulin Efficacy (DURABLE) Trial 24-Week Results

@inproceedings{Buse2009DURAbilityOB,
  title={DURAbility of Basal Versus Lispro Mix 75/25 Insulin Efficacy (DURABLE) Trial 24-Week Results},
  author={John B. Buse and Bruce H. R. Wolffenbuttel and William H Herman and Natalie K. Shemonsky and Honghua H. Jiang and Jessie L. Fahrbach and Jamie L Scism-Bacon and Sherry A. Martin},
  booktitle={Diabetes care},
  year={2009}
}
  • John B. Buse, Bruce H. R. Wolffenbuttel, +5 authors Sherry A. Martin
  • Published in Diabetes care 2009
  • Medicine
  • OBJECTIVE To compare the ability of two starter insulin regimens to achieve glycemic control in a large, ethnically diverse population with type 2 diabetes. RESEARCH DESIGN AND METHODS During the initiation phase of the DURABLE trial, patients were randomized to a twice-daily lispro mix 75/25 (LM75/25; 75% lispro protamine suspension, 25% lispro) (n = 1,045) or daily glargine (GL) (n = 1,046) with continuation of prestudy oral antihyperglycemic drugs. RESULTS Baseline A1C was similar (LM75… CONTINUE READING

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