DTI correlates of cognition in term children with spastic diplegic cerebral palsy.

  title={DTI correlates of cognition in term children with spastic diplegic cerebral palsy.},
  author={Yogita Rai and Saurabh Chaturvedi and Vimal Kumar Paliwal and Puneet Goyal and Ankita Chourasia and Ram Kishore Singh Rathore and Abhishek Yadav and Chandra Mani Pandey and Rakesh Lalla and Ravindra Kumar Garg and Rakesh K. Gupta},
  journal={European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society},
  volume={17 3},
  • Y. RaiSaurabh Chaturvedi Rakesh K. Gupta
  • Published 1 May 2013
  • Medicine, Psychology
  • European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society

Spatial Patterns of Whole Brain Grey and White Matter Injury in Patients with Occult Spastic Diplegic Cerebral Palsy

Using voxel-based morphometry and tract-based spatial statistics analysis, spatial patterns of whole brain grey and white matter injury in occult SDCP were revealed and several regions of white matter tracts injury were found to be significantly correlated with motor dysfunction.

Regional vulnerability of longitudinal cortical association connectivity

Cortical Somatosensory Reorganization in Children with Spastic Cerebral Palsy: A Multimodal Neuroimaging Study

The findings suggest an abnormal SS processing mechanism in the sensorimotor network of children with CP possibly as a result of diminished thalamocortical projections.

Whole‐brain structural connectivity in dyskinetic cerebral palsy and its association with motor and cognitive function

A disruption in structural brain connectivity in dyskinetic CP is demonstrated, revealing general involvement of posterior brain regions with relative preservation of prefrontal areas and pathways in which WM integrity is related to clinical features, including but not limited to the sensorimotor system.

Cognitive functioning in dyskinetic cerebral palsy: Its relation to motor function, communication and epilepsy.

Reorganization of the somatosensory cortex in hemiplegic cerebral palsy associated with impaired sensory tracts



Comparing quantitative tractography metrics of motor and sensory pathways in children with periventricular leukomalacia and different levels of gross motor function

Children with bilateral spastic CP with differing levels of gross motor function have corresponding differences detectable on DTT in their corticospinal tracts but not in their somatosensory tracts and posterior thalamic radiations.

Diffusion Tensor Imaging in Children with Periventricular Leukomalacia: Variability of Injuries to White Matter Tracts

The tract-specific evaluation of diffusion tensor imaging revealed a family of tracts that are highly susceptible in PVL, important information that can potentially be used to tailor treatment options in the future.

Cognitive Profiles and Visuoperceptual Abilities in Preterm and Term Spastic Diplegic Children With Periventricular Leukomalacia

The authors conclude that the management of preterm and term children should differ, with concentration on visuoperceptual skills and rehabilitation in the former.

Brain lesions in preterms: origin, consequences and compensation

High‐risk preterm born children, from a cohort with cerebral blood flow measurements in the first 2 d of life, were examined prospectively at the age of 5.5—7 y neurologically, neuropsychologically and by magnetic resonance imaging (MRI), showing specific morphological correlates for the major disabilities.

Diffusion tensor images in children with early-treated, chronic, malignant phenylketonuric: correlation with intelligence assessment.

Though treated early, patients with chronic, stable malignant PKU had abnormal DT findings in the parieto-occipital central white matter, suggesting EV2, EV3, and FA maps are potential tools for demonstrating brain changes due to malignantPKU.

Neuroimaging in Cerebral Palsy: Patterns of Brain Dysgenesis and Injury

  • A. Hoon
  • Medicine, Psychology
    Journal of child neurology
  • 2005
Improved understanding of pathogenesis, especially in regard to periventricular leukomalacia and hypoxic-ischemic encephalopathy, might lead to interventions preventing brain injury in preterm infants and asphyxiated term newborns.

Sensory and motor deficits in children with cerebral palsy born preterm correlate with diffusion tensor imaging abnormalities in thalamocortical pathways

This work investigated the relationship between DTI‐observed thalamocortical (posterior thalamic radiation) injury, motor (corticospinal tract) attack, and sensorimotor function.

Cognitive Outcome of Children With Early-Onset Hemiparesis

Overall, the patients showed impairment in many cortical functions and diffuse cognitive delay compared to controls and the side of lesion, active epilepsy, and male gender were significant factors in predicting cognitive outcome.