DSG3 as a biomarker for the ultrasensitive detection of occult lymph node metastasis in oral cancer using nanostructured immunoarrays.

@article{Patel2013DSG3AA,
  title={DSG3 as a biomarker for the ultrasensitive detection of occult lymph node metastasis in oral cancer using nanostructured immunoarrays.},
  author={Vyomesh S. Patel and Daniel Martin and Ruchika Malhotra and Christina A Marsh and Colleen L Doçi and Timothy D. Veenstra and Cherie-Ann O Nathan and Uttam K. Sinha and Bhuvanesh Singh and Alfredo A Molinolo and James F. Rusling and J. Silvio Gutkind},
  journal={Oral oncology},
  year={2013},
  volume={49 2},
  pages={93-101}
}
OBJECTIVES The diagnosis of cervical lymph node metastasis in head and neck squamous cell carcinoma (HNSCC) patients constitutes an essential requirement for clinical staging and treatment selection. However, clinical assessment by physical examination and different imaging modalities, as well as by histological examination of routine lymph node cryosections can miss micrometastases, while false positives may lead to unnecessary elective lymph node neck resections. Here, we explored the… CONTINUE READING
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