DR antigens expressed on tumor cells do not contribute to the blastogenetic response of autologous T cells

@article{Vnky1985DRAE,
  title={DR antigens expressed on tumor cells do not contribute to the blastogenetic response of autologous T cells},
  author={Farkas V{\'a}nky and Eva Klein and Jan Willems},
  journal={Cancer Immunology, Immunotherapy},
  year={1985},
  volume={19},
  pages={219-225}
}
Tumor cell suspensions prepared from surgical specimens were characterized for cellular composition and reactivity with monoclonal antibodies detecting T lymphocytes, monocytes, and the monomorphic determinants of DR molecules (antigens encoded by the D region of the major histocompatibility complex in man). About half the adenocarcinoma preparations contained tumor cells which expressed DR antigens. Lymphocytes of certain patients were stimulated in vitro by the autologous tumor cells, and… CONTINUE READING
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