DPPIV/CD26: a tumor suppressor or a marker of malignancy?

  title={DPPIV/CD26: a tumor suppressor or a marker of malignancy?},
  author={Aline Beckenkamp and Samuel Ingraham Davies and J{\'u}lia Biz Willig and Andr{\'e}ia Buffon},
  journal={Tumor Biology},
Dipeptidyl peptidase IV (DPPIV/CD26) is a multifunctional protein with intrinsic peptidase activity that inactivates or degrades some bioactive peptides. It is the main cellular binding protein for ecto-adenosine deaminase and interacts with extracellular matrix proteins, besides participating in different signaling pathways. Due to these multiple functions, DPPIV/CD26 has been shown to be closely related to the tumor process. It has been reported that the progression of certain types of cancer… CONTINUE READING


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