DOPA effects on motility in mice; Potentiation by MK 485 and dexchlorpheniramine

@article{Strmberg1970DOPAEO,
  title={DOPA effects on motility in mice; Potentiation by MK 485 and dexchlorpheniramine},
  author={Ulf Str{\"o}mberg},
  journal={Psychopharmacologia},
  year={1970},
  volume={18},
  pages={58-67}
}
Mice were given L-DOPA i.p. in doses ranging from 7.8 to 500 mg/kg with and without previous administration of MK 485, a compound capable of inhibiting extracerebral dopa decarboxylase. In addition, dexchlorpheniramine together with MK 485 was given before L-DOPA to some of the animals. Spontaneous locomotor activity of the animals was measured and some… CONTINUE READING