DOG1 for the diagnosis of gastrointestinal stromal tumor (GIST): Comparison between 2 different antibodies.

@article{Lopes2010DOG1FT,
  title={DOG1 for the diagnosis of gastrointestinal stromal tumor (GIST): Comparison between 2 different antibodies.},
  author={Lisandro Ferreira Lopes and Robert B. West and L{\'i}via M Bacchi and Matt van de Rijn and Carlos Eduardo Bacchi},
  journal={Applied immunohistochemistry & molecular morphology : AIMM},
  year={2010},
  volume={18 4},
  pages={333-7}
}
Gastrointestinal stromal tumor (GIST) is the most common mesenchymal neoplasm of the gastrointestinal tract. Discovered on GIST-1 (DOG1) is a recently described protein expressed in GISTs irrespective of mutation status. The aim of this study was to investigate the immunohistochemical expression of DOG1 using 2 different monoclonal antibodies (DOG1.1 and the commercially available K9 antibody) in 668 GIST cases and to compare the results with the expression of KIT. DOG1 and KIT expression also… CONTINUE READING
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Efficacy and safety of sunitinib in patients with advanced gastrointestinal stromal tumour after failure of imatinib: a randomized controlled trial

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